One general tied to the Seleucid Empire was Artaxias, who founded the Artaxiad dynasty and managed to unite various Armenian regions under his rule and establish a strong central government, which enabled him to wage successful military campaigns against neighbouring powers. Artaxias I the Pious also built the capital city of Artaxata, which became a cultural and economic centre for the Armenian people. The succeeding kings of the Artaxiad dynasty continued to expand the territory of Greater Armenia, which at its height, stretched from the Black Sea to the Caspian Sea and from the Caucasus Mountains to the Mediterranean Sea.

During the reign of the Artaxiad dynasty, Armenia became a hub of trade and commerce, connecting the Silk Road and the Mediterranean world. The Armenian kings encouraged the development of agriculture, commerce, and arts, and the kingdom became renowned for its skilled artisans, writers, and philosophers. Of course, given its central location, the dynasty also faced numerous challenges, including repeated invasions by the Roman and Parthian empires, internal conflicts, and economic hardships. The dynasty’s resilience and adaptability enabled it to survive for nearly two centuries, leaving behind a rich cultural and political legacy that has endured in the region, even as its historical memory was overshadowed by its more powerful neighbors.

Today, the Artaxiad dynasty remains an integral part of the Armenian identity, and its influence can be found in Armenian art, literature, music, and architecture. Perhaps just as importantly, the dynasty continues to inspire Armenian patriotism to this day. Many literary works have been written about the kings of the Artaxiad dynasty, including novels, plays, and poems, and many operas have been written about the most powerful king of the dynasty, Tigran II the Great (Tigranes II), including one written by the famed composer Antonia Vivaldi, Tigrane.